He that refuseth instruction
The instruction of parents, masters, ministers, and of God himself; or "correction" F25, instruction either by the word or by the rod; he that withdraws himself from it, will not be in the way of it, that shuns, neglects, and despises it, or carelessly and contemptuously attends it: despiseth his own soul;
shows that he makes no account of it, has no regard for it or care about it, when it is so precious a jewel, and the loss of it irreparable; not that a man can strictly and properly despise his soul, but comparatively, having a greater regard for his body, and especially for his carnal lusts and pleasures, than for that; or as a man diseased and refuses proper medicines may be said to despise his health; but he that heareth reproof getteth understanding;
or "a heart" F26; he gets understanding by listening to reproof, and behaving according to it; he better understands himself and his case, what he should shun and avoid, what he should receive, embrace, and do; instead of losing his soul, as the man that refuses correction does, he finds the life of it, and possesses it, and with it a large share of experience and spiritual wisdom.
The Brenton translation of the Septuagint is in the public domain.