[As] with a sword in my bones, mine enemies reproach me
The reproaches of his enemies were grievous and cutting to him, as if a sword pierced through the marrow in his bones, which, being very sensitive, gives exquisite pain. There is a various reading here: some copies, as Vatablus observes, read (b) , "in", or with, and others (k) , "as", which seems to be the truest; and our translators supply "as", to make the sense, though they read "with"; but some F14 only read "as"; and the sense is, the reproaches cast upon the psalmist were as a sword cutting and killing; and these reproaches were as follow;
while they say daily unto me, where [is] thy God?
(See Gill on Psalms 42:3).