Deuteronomy 29:21

21 And utterly destroy him out of all the tribes of Israel, according to the curses that are contained in the book of this law and covenant:

Deuteronomy 29:21 Meaning and Commentary

Deuteronomy 29:21

And the Lord shall separate him unto evil out of all the
tribes of Israel
Unto the evil of punishment, devote and consign him to it, and make him a visible and distinguished mark of his displeasure and vengeance. So some men are righteously separated from others, and preordained unto condemnation, being wicked and ungodly men; for such God has made or appointed for the day of evil; see ( Proverbs 16:4 ) ( Jude 1:4 ) ;

according to all the curses of the covenant that are written in this
book of the law;
the evil of punishment he shall be separated unto shall be according to them, or include them all; the sense is, that the wrath of God, and the whole curse of the law due to him for his sin, shall come upon him; see ( Deuteronomy 28:16-18 )

Deuteronomy 29:21 In-Context

19 And when he shall hear the words of this oath, he should bless himself in his heart saying: I shall have peace, and will walk on in the naughtiness of my heart: and the drunken may consume the thirsty,

20 And the Lord should not forgive him: but his wrath and jealousy against that man should be exceedingly enkindled at that time, and all the curses that are written in this volume should light upon him: and the Lord should blot out his name from under heaven,

21 And utterly destroy him out of all the tribes of Israel, according to the curses that are contained in the book of this law and covenant:

22 And the following generation shall say, and the children that shall be born hereafter, and the strangers that shall come from afar, seeing the plagues of that land and the evils wherewith the Lord hath afflicted it,

23 Burning it with brimstone, and the heat of salt, so that it cannot be sown any more, nor any green thing grow therein, after the example of the destruction of Sodom and Gomorrha, Adama and Seboim, which the Lord destroyed in his wrath and indignation: