Jeremiah 49:24

Damascus is waxed feeble
Or, "is become remiss" ^F7; her hands hang down, not being able through fear and fright to lift them up against the enemy; that is, the inhabitants of Damascus, as the Targum: [and] turneth herself to flee;
instead of going out to meet the enemy, the inhabitants of this city meditated a flight, and turned their backs upon him in order to flee from him, and escape falling into his hands: and fear hath seized on [her]:
or, "she seized on fear" ^F8; instead of seizing on arms, and laying hold on them to defend herself with, she seized on that; or however that seized on her, and made her quite unfit to stand up in her own defence: anguish and sorrows have taken her as a woman in travail;
(See Gill on Jeremiah 49:22); A phrase often used to express the sudden and inevitable destruction of a people, and their distress and inability to help themselves.