Psalms 109:22

For I am poor and needy
As he was in human nature, being born of poor parents, brought up in a mean manner, had not where to lay his head, and was ministered to by others; though he was Lord of all, and immensely rich in the perfections of his nature, and in his vast empire and dominion, and the revenues arising from thence; see ( 2 Corinthians 8:9 ) . It may here chiefly respect his helpless and forlorn estate as man, at the time of his sufferings and death; see ( Psalms 40:17 ) .

And my heart is wounded within me;
with the sins of his people on him, with a sense of divine wrath, and when under divine desertions, especially when his soul was exceeding sorrowful, even unto death, ( Matthew 26:38 ) ( Psalms 40:12 ) .