Psalms 143:4

Therefore is my spirit overwhelmed within me
Covered over with grief, borne down with sorrow, ready to sink and fail; (See Gill on Psalms 142:3);

my heart within me is desolate;
destitute of the spirit and presence of God, and with respect to the exercise of grace, and filled with fears and misgivings; or "astonished" ^F21, at the providence he was under, like one stunned and filled with sore amazement, not knowing what to make of things, or what the issue of them would be; so David's antitype was "sore amazed" in the garden, when his troubles and agonies came upon him, ( Mark 14:33 ) .