Deuteronomy 29:21

21 And Yahweh will single him out for calamity out of all the tribes of Israel, according to all the curses of the covenant written in the scroll of this law.

Deuteronomy 29:21 Meaning and Commentary

Deuteronomy 29:21

And the Lord shall separate him unto evil out of all the
tribes of Israel
Unto the evil of punishment, devote and consign him to it, and make him a visible and distinguished mark of his displeasure and vengeance. So some men are righteously separated from others, and preordained unto condemnation, being wicked and ungodly men; for such God has made or appointed for the day of evil; see ( Proverbs 16:4 ) ( Jude 1:4 ) ;

according to all the curses of the covenant that are written in this
book of the law;
the evil of punishment he shall be separated unto shall be according to them, or include them all; the sense is, that the wrath of God, and the whole curse of the law due to him for his sin, shall come upon him; see ( Deuteronomy 28:16-18 )

Deuteronomy 29:21 In-Context

19 And then when he hears the words of this oath, then {he will assure himself} in his heart, {saying}, '{Safety shall be mine even though I go in the stubbornness of my heart},' thereby destroying the well-watered [land] [along] with the parched.

20 Yahweh will not be willing to forgive him, for [by then] the anger of Yahweh will smoke, and his passion against that man and all the curses written in this scroll will descend on him, and Yahweh will blot out his name from under heaven.

21 And Yahweh will single him out for calamity out of all the tribes of Israel, according to all the curses of the covenant written in the scroll of this law.

22 "And the next generation, [that is], your children who will rise [up] after you, and the foreigner who will come from a distant land, when they will see the plagues of that land and its diseases that Yahweh has inflicted upon it, will say,

23 'All its land is brimstone and salt left by fire, {none of its land will be sown}, and it will not make plants sprout out and it will not grow any vegetation; [it is] as the destruction of Sodom and Gomorrah, Adman and Zeboiim, which Yahweh overturned in his anger and in his wrath.'