Matthew 19:4; Matthew 19:8; Matthew 24:8; Matthew 24:21

4 And He answered and said, "Have you not read that He who created them from the beginning MADE THEM MALE AND FEMALE,
8 He said to them, "Because of your hardness of heart Moses permitted you to divorce your wives; but from the beginning it has not been this way.
8 "But all these things are merely the beginning of birth pangs.
21 "For then there will be a great tribulation, such as has not occurred since the beginning of the world until now, nor ever will.