Isaiah 59:2

2 But your iniquities have been separating Between you and your God, And your sins have hidden The Presence from you -- from hearing.

Isaiah 59:2 Meaning and Commentary

Ver. 2 But your iniquities have separated between you and your God,
&c.] Like a partition wall dividing between them, so that they enjoy no communion with him in his worship and ordinances; which is greatly the case of the reformed churches: they profess the true God, and the worship of him, and do attend the outward ordinances of it; but this is done in such a cold formal way, and such sins and wickedness are perpetrated and connived at, that the Lord does not grant his gracious presence to them, but stands at a distance from them: and your sins have hid his face from you,
that he will not hear; or have caused him to hide himself; withdraw his gracious presence; neglect the prayers put up to him; deny an answer to them; or, however, not appear as yet for the deliverance and salvation of them, and bringing them into a more comfortable, prosperous, and happy condition.

Isaiah 59:2 In-Context

1 Lo, the hand of Jehovah Hath not been shortened from saving, Nor heavy his ear from hearing.
2 But your iniquities have been separating Between you and your God, And your sins have hidden The Presence from you -- from hearing.
3 For your hands have been polluted with blood, And your fingers with iniquity, Your lips have spoken falsehood, Your tongue perverseness doth mutter.
4 There is none calling in righteousness, And there is none pleading in faithfulness, Trusting on emptiness, and speaking falsehood, Conceiving perverseness, and bearing iniquity.
5 Eggs of a viper they have hatched, And webs of a spider they weave, Whoso is eating their eggs doth die, And the crushed hatcheth a viper.
Young's Literal Translation is in the public domain.