Revelation 9:18

18 by these three were the third of men killed, from the fire, and from the smoke, and from the brimstone, that is proceeding out of their mouth,

Revelation 9:18 Meaning and Commentary

Revelation 9:18

And by these three was the third part of men killed
The Alexandrian copy, and some others, the Complutensian edition, the Vulgate Latin, Syriac, and Ethiopic versions, read, "by these three plagues": as the western Roman empire is in the preceding chapter frequently expressed by the third part of several things, see ( Revelation 8:7-12 ) ; so here the eastern Roman empire by the third part of men; vast numbers of the inhabitants of which were destroyed by the Turks, through the use of guns, out of which issued fire, smoke, and brimstone; and Constantinople, the metropolis of it, was taken in this way, as before observed, with the taking of which the empire ceased.

By the fire, and by the smoke, and by the brimstone, which issued
out of their mouths;
that is, by the firing of guns.

Revelation 9:18 In-Context

16 and the number of the forces of the horsemen [is] two myriads of myriads, and I heard the number of them.
17 And thus I saw the horses in the vision, and those sitting upon them, having breastplates of fire, and jacinth, and brimstone; and the heads of the horses [are] as heads of lions, and out of their mouths proceedeth fire, and smoke, and brimstone;
18 by these three were the third of men killed, from the fire, and from the smoke, and from the brimstone, that is proceeding out of their mouth,
19 for their authorities are in their mouth, and in their tails, for their tails [are] like serpents, having heads, and with them they do injure;
20 and the rest of men, who were not killed in these plagues, neither did reform from the works of their hands, that they may not bow before the demons, and idols, those of gold, and those of silver, and those of brass, and those of stone, and those of wood, that are neither able to see, nor to hear, nor to walk,
Young's Literal Translation is in the public domain.