1 Now the Spirit speaketh expressly, that in the latter times some shall depart from the faith, giving heed to seducing spirits, and doctrines of devils;
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The Spirit clearly says that in later times some will abandon the faith and follow deceiving spirits and things taught by demons.
2 Speaking lies in hypocrisy; having their conscience seared with a hot iron;
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Such teachings come through hypocritical liars, whose consciences have been seared as with a hot iron.