Psalms 109:2-12

2 For the mouth of the wicked and the mouth of deceit have they opened against me: They have spoken unto me with a lying tongue.
3 They have compassed me about also with words of hatred, And fought against me without a cause.
4 For my love they are my adversaries: But I [give myself unto] prayer.
5 And they have rewarded me evil for good, And hatred for my love.
6 Set thou a wicked man over him; And let an adversary stand at his right hand.
7 When he is judged, let him come forth guilty; And let his prayer be turned into sin.
8 Let his days be few; [And] let another take his office.
9 Let his children be fatherless, And his wife a widow.
10 Let his children be vagabonds, and beg; And let them seek [their bread] out of their desolate places.
11 Let the extortioner catch all that he hath; And let strangers make spoil of his labor.
12 Let there be none to extend kindness unto him; Neither let there be any to have pity on his fatherless children.

Psalms 109:2-12 Meaning and Commentary

To the chief Musician, A Psalm of David. This psalm was written by David, under the inspiration of the Holy Spirit, concerning Judas the betrayer of Christ, as is certain from Acts 1:16 hence it is used to be called by the ancients the Iscariotic psalm. Whether the occasion of it was the rebellion of Absalom, as some, or the persecution of Saul, as Kimchi; and whoever David might have in view particularly, whether Ahithophel, or Doeg the Edomite, as is most likely; yet it is evident that the Holy Ghost foresaw the sin of Judas, and prophesies of that, and of the ruin and misery that should come upon him; for the imprecations in this psalm are no other than predictions of future events, and so are not to be drawn into an example by men; nor do they breathe out anything contrary to the spirit of Christianity, but are proofs of it, since what is here predicted has been exactly accomplished. The title in the Syriac version is, "a psalm of David when they created Absalom king without his knowledge, and for this cause he was slain; but to us it expounds the sufferings of the Christ of God;" and indeed he is the person that is all along speaking in this psalm.
The American Standard Version is in the public domain.