Deuteronomy 16:4

4 For seven days no one in your land is to have any yeast in the house; and the meat of the animal killed on the evening of the first day must be eaten that same night.

Deuteronomy 16:4 Meaning and Commentary

Deuteronomy 16:4

And there shall be no leavened bread seen with thee in all thy
coasts seven days
For before the passover they were to search diligently every room in the house, and every hole and crevice, that none might remain any where; see ( Exodus 12:15 Exodus 12:19 ) ( 13:7 ) ,

neither shall there be anything of the flesh, which thou sacrificedst
the first day at even, remain all night until the morning;
which may be understood both of the flesh of the passover lamb, as Aben Ezra, according to ( Exodus 12:10 ) and of the flesh of flocks and herds, or of the Chagigah; according to Jarchi this Scripture speaks of the Chagigah of the fourteenth, which was not to remain on the first day of the feast (the fifteenth) until the morning of the second day (the sixteenth).

Deuteronomy 16:4 In-Context

2 Go to the one place of worship and slaughter there one of your sheep or cattle for the Passover meal to honor the Lord your God.

3 When you eat this meal, do not eat bread prepared with yeast. For seven days you are to eat bread prepared without yeast, as you did when you had to leave Egypt in such a hurry. Eat this bread - it will be called the bread of suffering - so that as long as you live you will remember the day you came out of Egypt, that place of suffering.

4 For seven days no one in your land is to have any yeast in the house; and the meat of the animal killed on the evening of the first day must be eaten that same night.

5 "Slaughter the Passover animals at the one place of worship - and nowhere else in the land that the Lord your God will give you. Do it at sunset, the time of day when you left Egypt.