Ephesians 6:18

18 Do all this in prayer, asking for God's help. Pray on every occasion, as the Spirit leads. For this reason keep alert and never give up; pray always for all God's people.

Ephesians 6:18 Meaning and Commentary

Ephesians 6:18

Praying always with all prayer and supplication in the
spirit
The last weapon is prayer, and takes in all sorts of prayer, mental and vocal, public and private; and every branch of it, as deprecation of evils, petitions for good things, and thanksgiving for mercies: and which should be used always: this stands opposed to such who pray not at all, or who have prayed, but have left it off; or who pray only in distress, and it suggests, that a man should pray as often as he has an opportunity; and particularly, that he should make use of it in times of darkness, desertion, and temptation: and this, when performed aright, is performed "in the Spirit"; with the heart, soul, and spirit engaged in it; it is put up with a true heart, and a right spirit, and without hypocrisy; in a spiritual way, and with fervency, and under the influence, and by the assistance of the Spirit of God.

And watching thereunto;
either to the word, as a direction for prayer, or to prayer itself; for opportunities to pray for the assistance of the Spirit in prayer, for an answer of it, and to return thanks for blessings when bestowed; and against all dependence on it, and against Satan's temptations, and our own corruptions with respect to it:

with all perseverance;
in it, notwithstanding what Satan and an unbelieving heart may suggest to the contrary:

and supplication for all saints;
of every nation, age, sex, and condition, in all places, and of every denomination. So Christ taught his disciples to pray, saying, our Father, suggesting, that they were not only to pray for themselves, but for all the children of God.

Ephesians 6:18 In-Context

16 At all times carry faith as a shield; for with it you will be able to put out all the burning arrows shot by the Evil One.
17 And accept salvation as a helmet, and the word of God as the sword which the Spirit gives you.
18 Do all this in prayer, asking for God's help. Pray on every occasion, as the Spirit leads. For this reason keep alert and never give up; pray always for all God's people.
19 And pray also for me, that God will give me a message when I am ready to speak, so that I may speak boldly and make known the gospel's secret.
20 For the sake of this gospel I am an ambassador, though now I am in prison. Pray that I may be bold in speaking about the gospel as I should.
Scripture taken from the Good News Translation - Second Edition, Copyright 1992 by American Bible Society. Used by Permission.