Genesis 17:21

21 But I will establish my covenant with Isaac, whom Sarrha shall bear to thee at this time, in the next year.

Genesis 17:21 Meaning and Commentary

Genesis 17:21

But my covenant will one establish with Isaac
The covenant of circumcision; for though Ishmael was circumcised, and his posterity practised that rite, yet it was not enjoined them of God; nor was it to them, or served the same purpose as to the Israelites; and particularly the promise of the land of Canaan, made in that covenant, belonged only to the posterity of Isaac, and to those only in the line of Jacob, and especially that of the Messiah springing from him, which circumcision had a respect unto:

whom Sarah shall bear unto thee, at this set time, in the next year:
that is, at the end of nine months, which is the set time a woman goes with child.

Genesis 17:21 In-Context

19 And God said to Abraam, Yea, behold, Sarrha thy wife shall bear thee a son, and thou shalt call his name Isaac; and I will establish my covenant with him, for an everlasting covenant, to be a God to him and to his seed after him.
20 And concerning Ismael, behold, I have heard thee, and, behold, I have blessed him, and will increase him and multiply him exceedingly; twelve nations shall he beget, and I will make him a great nation.
21 But I will establish my covenant with Isaac, whom Sarrha shall bear to thee at this time, in the next year.
22 And he left off speaking with him, and God went up from Abraam.
23 And Abraam took Ismael his son, and all his home-born , and all those bought with money, and every male of the men in the house of Abraam, and he circumcised their foreskins in the time of that day, according as God spoke to him.

The Brenton translation of the Septuagint is in the public domain.