Deliver me from all my transgressions
Which were the cause and occasion of all his distresses, inward and outward; and the deliverance prayed for includes a freedom from the dominion of sin, which is by the power of efficacious grace; and from the guilt of sin, which is by the application of the blood of Christ; and from obligation to punishment for it, or deliverance from wrath to come, which is through Christ's being made a curse, and enduring wrath in the room and stead of his people; and from the very being of sin, which, though it cannot be expected in this life, is desirable: and the psalmist prays that he might be delivered from "all" his transgressions; knowing: that if one of them was left to have dominion over him, or the guilt of it to lie upon him, and he be obliged to undergo due punishment for it, he must be for ever miserable;
make me not the reproach of the foolish;
of a Nabal; meaning not any particular person; as Esau, according to Jarchi; or Absalom, as others; but every foolish man, that is, a wicked man; such who deny the being and providence of God, make a mock at sin, and scoff at the saints: and the sense of the psalmist is, that the Lord would keep him from sinning, and deliver him out of all his afflictions, on account of which he was reproached by wicked men.