Revelation 16:6

6 because blood of saints and prophets they did pour out, and blood to them Thou didst give to drink, for they are worthy;'

Revelation 16:6 Meaning and Commentary

Revelation 16:6

For they have shed the blood of saints and prophets
Which shows that rivers and fountains cannot be literally understood, but men are designed, wicked and bloody men; and it is notorious to all, how much of the blood of the saints, of the preachers of the Gospel, of the prophets and witnesses, have been shed in Italy, Savoy, and other places near Rome, as well as in Rome itself; see ( Revelation 17:6 ) ( 18:24 ) .

And thou hast given them blood to drink;
sent the sword among them, making great slaughter and devastation; see ( Isaiah 49:26 )

for they are worthy;
or deserving, to have their blood shed by the law of retaliation.

Revelation 16:6 In-Context

4 And the third messenger did pour out his vial to the rivers, and to the fountains of the waters, and there came blood,
5 and I heard the messenger of the waters, saying, `righteous, O Lord, art Thou, who art, and who wast, and who shalt be, because these things Thou didst judge,
6 because blood of saints and prophets they did pour out, and blood to them Thou didst give to drink, for they are worthy;'
7 and I heard another out of the altar, saying, `Yes, Lord God, the Almighty, true and righteous [are] Thy judgments.'
8 And the fourth messenger did pour out his vial upon the sun, and there was given to him to scorch men with fire,
Young's Literal Translation is in the public domain.