Daniel 7:21

21 I beheld, and that horn made war with the saints, and prevailed over them;

Daniel 7:21 Meaning and Commentary

Daniel 7:21

I beheld, and the same horn made war with the saints
The same little horn before described; not Antiochus Epiphanes, who made war with the Jews, as many think; or the Roman Caesars, that persecuted the church of Christ, as others; nor Titus Vespasian, who fought against Israel, as Saadiah; but antichrist, or the pope of Rome; and this refers to the wars of the popes with the Waldenses, which began in the year 1160, and continued long, and with the two witnesses at the close of their testimony, ( Revelation 11:7 ) ( 13:7 ) , this Daniel had a view of in vision; not while he was inquiring of the angel, but before, though not mentioned till now; and was a reason he was so very inquisitive about this little horn, because of its war with the saints, and its success, as follows: and prevailed against them:
as the popes and their abettors did against the Waldenses and Albigenses, whom they slew in great numbers, and got the victory over; as the beast also, the same with this little horn, will overcome the witnesses, and slay them, ( Revelation 11:7 ) .

Daniel 7:21 In-Context

19 Then I desired to know the certainty concerning the fourth beast, which was different from them all, exceeding dreadful, whose teeth were of iron, and its nails of brass; which devoured, broke in pieces, and stamped the rest with its feet;
20 and concerning the ten horns that were in its head, and the other that came up, and before which three fell: even that horn that had eyes, and a mouth speaking great things, and whose look was more imposing than its fellows.
21 I beheld, and that horn made war with the saints, and prevailed over them;
22 until the Ancient of days came, and judgment was given to the saints of the most high [places]; and the appointed time arrived, and the saints possessed the kingdom.
23 He said thus: The fourth beast shall be a fourth kingdom upon the earth, which shall be different from all the kingdoms, and shall devour the whole earth, and shall tread it down, and break it in pieces.
The Darby Translation is in the public domain.