Isaiah 14:22

22 And I shall rise [up] on them, saith the Lord of hosts, and I shall lose the name of Babylon, and the remnants, and generation, and seed, saith the Lord. (For I shall rise up against them, saith the Lord of hosts, and I shall destroy the name of Babylon, and its remnants, and its children, and its descendants, saith the Lord.)

Isaiah 14:22 Meaning and Commentary

Isaiah 14:22

For I will rise up against them, saith the Lord of hosts,
&c.] That is, against the children of the Babylonish monarch; and therefore they shall not rise and possess the earth, and disturb it, since he who is the Lord of armies in heaven and earth, and has all power in both worlds, and has everything at his beck and command, will rise up, who seemed, as it were, asleep, and unconcerned about the affairs of this world, and will set himself against them, and exert his power in their destruction: and cut off from Babylon;
the king of Babylon, and the inhabitants of it: the name;
not of the city, which is mentioned long after, and still is; but of the king and his family: and remnant;
his flesh, or those that were akin to him, as Kimchi interprets it: and son, and nephew;
his son, and son's son as the Targum, and after that other Jewish writers; the whole family was destroyed with Belshazzar, after whom none of that race was ever heard of any more.

Isaiah 14:22 In-Context

20 thou shalt not have fellowship, neither with them in sepulchre, for thou hast lost thy land, thou hast slain the people; the seed of the worst men shall not be called without end. (thou shalt not have fellowship with them in the tomb, or in the grave, for thou hast destroyed thy land, and thou hast killed thy own people; the children, or the descendants, of these evil people shall never be seen again.)

21 Make ye ready his sons to slaying, for the wickedness of their fathers; they shall not rise, neither they shall inherit the land, neither they shall fill the face of the roundness (of the earth) of cities. (Prepare ye his sons for killing, for the wickedness of their forefathers; they shall not rise up and inherit the land, nor shall they fill the face of the roundness of the earth with their cities.)

22 And I shall rise [up] on them, saith the Lord of hosts, and I shall lose the name of Babylon, and the remnants, and generation, and seed, saith the Lord. (For I shall rise up against them, saith the Lord of hosts, and I shall destroy the name of Babylon, and its remnants, and its children, and its descendants, saith the Lord.)

23 And I shall set that Babylon into possession of an urchin, and into marishes of waters; and I shall sweep it with a besom, and I shall stamp (it), saith the Lord of hosts. (And I shall give that Babylon into the possession of hedgehogs, or of conies, and to the marshes of water; and I shall sweep it with a broom, and I shall stamp it, saith the Lord of hosts.)

24 The Lord of hosts swore, saying, Whether it shall not be so, as I guessed, and it shall befall so, as I treated in soul? (The Lord of hosts swore, saying, Shall it not be so, just as I thought, and shall it not befall, just as I said?)