Deuteronomy 28:59

Then the Lord will make thy plagues wonderful
Visible, remarkable, distinguishable, and astonishing to all that see them:

and the plagues of thy seed;
for they were to continue, as they have done, With their posterity, age after age:

[even] great plagues, and of long continuance;
great as to quality and quantity, and firm, sure, lasting, and durable; the word used is rendered "sure" in ( Isaiah 55:3 ) ; sure by prophecy and in the event; and which when inflicted remained, as they have 1700 years; all which might be believed as certain, or what would certainly come to pass, and be depended on:

and sore sicknesses, and of long continuance;
besides those diseases mentioned ( Deuteronomy 28:27 Deuteronomy 28:35 ) ; or however others including them.