Hosea 4:6

My people are destroyed for lack of knowledge
This is not to be understood of those who are the Lord's people by special grace; for they cannot he destroyed, at least with everlasting destruction; God's love to them, his choice of them, covenant with them, the redemption of them by Christ, and the grace of God in them, secure them from such destruction: nor can they perish through want of knowledge; for though they are by nature as ignorant as others, yet it is the determinate will of God to bring them to the knowledge of the truth, in order to salvation; and that same decree which fixes salvation as the end, secures the belief of the truth as the means; and the covenant of grace provides for their knowledge of spiritual things, as well as other spiritual blessings; in consequence of which their minds are enlightened by the Spirit of wisdom and understanding, and they have the knowledge of God and Christ given them, which is life eternal. But this is to he understood of the people of the ten tribes of Israel, who were nationally and nominally the people of God, were so by profession; they called themselves the people of God; and though they were idolaters, yet they professed to worship God in their idols; and as yet God's "loammi" had not taken place upon them; he still sent his prophets among them, to reprove and reform them, and they were not as yet finally rejected by him, and cast out of their land. These may be said to be "destroyed", because they were threatened with destruction, and it was near at hand, they were just upon the brink of it; and because of the certainty of it, and this "through the lack of knowledge": either in the people, who were ignorant of God, his mind, and will, and worship, and without fear and reverence of him, which was the cause of all the abominations they ran into, for which they were threatened with ruin; or in the priests, whose business it was to teach and instruct the people; but instead of teaching them true doctrine, and the true, manner of worship, taught them false doctrine, and led them into superstition and idolatry; and so they perished through the default of the priests in performing their office; which sense is confirmed by what follows: because thou hast rejected knowledge, I will also reject thee, that
thou shall be no priest to me;
the priests that Jeroboam made were of the lowest of the people, ignorant and illiterate men, ( 1 Kings 12:31 ) ( 13:33 ) and they chose to continue such; they rejected with contempt and abhorrence, as the word signifies, the knowledge of God, and of all divine things; of the law of God, concerning what was to be done, or not to be done, by the people; and of all statutes and ordinances relating to divine worship, and the performance of the priestly office: and though there might be some of Aaron's line that continued in the land of Israel, and in their office; yet these affected the same ignorance, and therefore the Lord threatens them with a rejection from the priesthood; or, however, that they should be no priests to him, or in his account, but should be had in the utmost abhorrence and contempt, The word here used has a letter in it more than usual ^F19, which may signify the utter rejection of them, and the great contempt they were had in by the Lord; this was to take place, and did, at the captivity by Shalmaneser. Seeing thou hast forgotten the law of thy God:
which he had given them, who was their God by profession; and which they had forgot as if they never had read or learnt it; and so as not to observe and keep it themselves, nor teach and instruct others in it: I will also forget thy children;
have no regard to them, take no notice and care of them, as if they were never known by him; meaning either the people in general, their disciples and spiritual children; or else their natural children, who should be cut off, and not succeed them in the priesthood. The words are very emphatic, "I will forget them, even I" ^F20; which expresses the certainty of it more fully, as well as more clearly points at the justness of the retaliation.