Genesis 17:22

22 And when he had finished talking with him, God went up from Abraham.

Genesis 17:22 Meaning and Commentary

Genesis 17:22

And he left off talking; with him
After he had finished all he had to say to him at this time. It was great condescension in the divine Being to talk with a creature; it was wonderful grace and kindness to make such promises to him, as he did, and indulge him with answers of prayer and communion with him; but the highest enjoyments of God here are not lasting; uninterrupted communion with him is reserved for another world:

and God went up from Abraham;
from the earth, where he had been with Abraham, and ascended above him up to heaven, in a visible, and very likely in an human form, in which he descended: the Targums of Onkelos and Jonathan paraphrase it, "the glory of the Lord", the glorious Shechinah, the Lord of life and glory.

Genesis 17:22 In-Context

20 As for Ishmael, I have heard you; I will bless him and make him fruitful and exceedingly numerous; he shall be the father of twelve princes, and I will make him a great nation.
21 But my covenant I will establish with Isaac, whom Sarah shall bear to you at this season next year."
22 And when he had finished talking with him, God went up from Abraham.
23 Then Abraham took his son Ishmael and all the slaves born in his house or bought with his money, every male among the men of Abraham's house, and he circumcised the flesh of their foreskins that very day, as God had said to him.
24 Abraham was ninety-nine years old when he was circumcised in the flesh of his foreskin.