2 Timothy 3:6

For of this sort are they which creep into houses
Privily and unawares, in a clandestine manner, and insinuate themselves into families, by fawning and flattering, and under specious pretences to knowledge and virtue. The Syriac version uses a word, from whence comes (adlwx) , "Chulda", which signifies "a weasel"; suggesting, that their entrance into houses was like to the way of that creature, which is sometimes covered, and sometimes open: there was also a gate of the temple, which was called "Huldah"; whether there is any allusion in the word to that, may be inquired ^F11.

And lead captive silly women;
the coming of antichrist is after the working of Satan; as Satan attacked the woman, and not the man, and beguiled Eve and not Adam, so these his instruments and emissaries, work themselves into the affections of the weaker vessel, and into the weaker sort of women, as the diminutive word here used signifies; and gain upon them, instil their principles into them, attach them to their interests, captivate them to them, and lead them as they please:

laden with sins;
covered with them, full of them, and so ready to receive any set of principles that would encourage them to continue in them; or else were pressed down with a sense of them, their consciences being awakened, and they under some concern on account of them, and so fit persons for such deceivers to gain upon, by pretending to great sanctity and religion, and by providing them with pardons and indulgences, and putting them upon penance though the former sense seems most agreeable, and is confirmed by what follows,

led away with divers lusts.
The Alexandrian copy adds, "and pleasures"; that is, sinful ones; though this may be understood, not of unclean lusts, but of the itch and desire after new teachers, and new doctrines, and practices, which prevail in weak women, and by which they are governed and led away.