Mark 8:34

And when he had called the people unto him
Who, it seems, followed him out of Galilee, from Bethsaida, and these parts; for it was in the way from thence to Caesarea Philippi, that Christ had this conversation with his disciples; who walked together alone, the multitude following at some distance; and the private conversation being ended, Christ called, or beckoned to the people, to come nearer to him:

with his disciples also;
for what he was about to say, concerned them both:

whosoever will come after me;
in a spiritual sense, as this multitude did in a natural one, and which is the same as to be a disciple of his:

let him deny himself, and take up his cross, and follow me;
signifying, that his followers must deny themselves of worldly advantages, and suffer many things, as well as he, which he had been but just before acquainting his disciples with; (See Gill on Matthew 16:24).