Genesis 25:26

26 And after this came forth his brother, and his hand took hold of the heel of Esau; and she called his name Jacob. And Isaac was sixty years old when Rebecca bore them.

Genesis 25:26 Meaning and Commentary

Genesis 25:26

And after that came his brother out
Out of his mother's womb, either by his own strength, or by the help of the midwife: and his hand took hold on Esau's heel;
to pluck him back and get out first; and this was not casual, but was so ordered in Providence, and had a meaning and mystery in it: and his name was called Jacob;
by his parents and others, and that for the above reason, because he took his brother by the heel, which his name has the signification of, and Esau has respect to in ( Genesis 27:36 ) : and Isaac [was] threescore years old when she bare them;
and so it was twenty years after he had been married to her; so long was his faith tried and exercised about the promised seed that was to spring from him.

Genesis 25:26 In-Context

24 And the days were fulfilled that she should be delivered, and she had twins in her womb.
25 And the first came out red, hairy all over like a skin; and she called his name Esau.
26 And after this came forth his brother, and his hand took hold of the heel of Esau; and she called his name Jacob. And Isaac was sixty years old when Rebecca bore them.
27 And the lads grew, and Esau was a man skilled in hunting, dwelling in the country, and Jacob a simple man, dwelling in a house.
28 And Isaac loved Esau, because his venison was his food, but Rebecca loved Jacob.

The Brenton translation of the Septuagint is in the public domain.