And thou shalt have great sickness by disease of thy bowels,
 &c.] Which was a just retaliation to him, for having no bowels of compassion on his brethren whom he slew: 
 until thy bowels fall out by reason of the sickness day by day;
 that continuing day after day, and even year after year, the space of two years, as appears from ( 2 Chronicles 21:19 ) .