Genesis 4
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Abel's offering implies a previous instruction (cf) Genesis 3:21 for it was "by faith" Hebrews 11:4 and faith is taking God at His word; so that Cain's unbloody offering was a refusal of the divine way. But Jehovah made a last appeal to Cain Genesis 4:7 even yet to bring the required offering.
mark
i.e. for Cain's protection. The law of Genesis 9:6 was not yet enacted.
Nod
Lit. wandering.
builded a city
The first civilization, that which perished in the judgment of the Flood, was Cainitic in origin, character, and destiny. Every element of material civilization is mentioned in verses Genesis 4:16-22, city and pastoral life, and the development of arts and manufactures. Enoch, after whom the first city was named, means "teacher." The el termination of the names of Enoch's son and grandson shows that for a time the knowledge of Elohim was preserved, but this soon disappears Romans 1:21-23 . Adah means "pleasure," or "adornment"; Zillah, to "hide"; Lamech, "conqueror," or "wild man." (Cf) Romans 1:21-25 . (See Scofield "Genesis 6:4") . The Cainitic civilization may have been as splendid as that of Greece or Rome, but the divine judgment is according to the moral state, not the material. Genesis 6:5-7 .
to my wounding
Or, who wounded me. Cain had slain an unoffending man and yet was protected by Jehovah; how much more Lamech, who had slain in self-defence.
Seth
i.e. Sheth = appointed.
Enos i.e. mortal.
call upon the name Or, call themselves by the name of Jehovah. Contra. Genesis 12:8 ; 26:25 .