Isaiah 21:1

Overview - Isaiah 21
The prophet, bewailing the captivity of his people, sees in a vision the fall of Babylon by the Medes and Persians.
11 Edom, scorning the prophet, is moved to repentance.
13 The set time of Arabia's calamity.
Treasury of Scripture Knowledge

Isaiah 21:1  (King James Version)
The burden of the desert of the sea. As whirlwinds in the south pass through; so it cometh from the desert, from a terrible land.

The burden
The first ten verses of this chapter contain a prediction of the taking of Babylon by the Medes and Persians; which is here denominated "the desert of the sea," because the country around it, and especially towards the sea, was a great morass, often overflowed by the Tigris and Euphrates, and only rendered habitable by being drained by a number of canals.
13:1 17:1

the desert
13:20-22 14:23 Jeremiah 51:42

As whirlwinds
Job 37:9 ; Daniel 11:40 ; Zechariah 9:14

Isaiah 13:4 Isaiah 13:5 Isaiah 13:17 Isaiah 13:18 Ezekiel 30:11 ; 31:12