Daniel 7:21

21 I saw, and the same horn made war with the holy ones, and prevailed against them;

Daniel 7:21 Meaning and Commentary

Daniel 7:21

I beheld, and the same horn made war with the saints
The same little horn before described; not Antiochus Epiphanes, who made war with the Jews, as many think; or the Roman Caesars, that persecuted the church of Christ, as others; nor Titus Vespasian, who fought against Israel, as Saadiah; but antichrist, or the pope of Rome; and this refers to the wars of the popes with the Waldenses, which began in the year 1160, and continued long, and with the two witnesses at the close of their testimony, ( Revelation 11:7 ) ( 13:7 ) , this Daniel had a view of in vision; not while he was inquiring of the angel, but before, though not mentioned till now; and was a reason he was so very inquisitive about this little horn, because of its war with the saints, and its success, as follows: and prevailed against them:
as the popes and their abettors did against the Waldenses and Albigenses, whom they slew in great numbers, and got the victory over; as the beast also, the same with this little horn, will overcome the witnesses, and slay them, ( Revelation 11:7 ) .

Daniel 7:21 In-Context

19 Then I desired to know the truth concerning the fourth animal, which was diverse from all of them, exceedingly terrible, whose teeth were of iron, and its nails of brass; which devoured, broke in pieces, and stamped the residue with its feet;

20 and concerning the ten horns that were on its head, and the other [horn] which came up, and before which three fell, even that horn that had eyes, and a mouth that spoke great things, whose look was more stout than its fellows.

21 I saw, and the same horn made war with the holy ones, and prevailed against them;

22 until the ancient of days came, and judgment was given to the holy ones of Ha`Elyon, and the time came that the holy ones possessed the kingdom.

23 Thus he said, The fourth animal shall be a fourth kingdom on eretz, which shall be diverse from all the kingdoms, and shall devour the whole eretz, and shall tread it down, and break it in pieces.