Jeremiah 51:63

63 And when thou hast [ful]filled to read this book, thou shalt bind to it a stone, and thou shalt cast it forth into the midst of Euphrates; (And when thou hast finished reading this book, thou shalt bind it to a stone, and thou shalt throw it forth into the midst of the Euphrates River;)

Jeremiah 51:63 Meaning and Commentary

Jeremiah 51:63

And it shall be, when thou hast made an end of reading this
book
To the captive Jews; and having also said the above words by way of prayer and approbation: [that] thou shalt bind a stone to it, and cast it into the midst of
Euphrates;
a river by which Babylon was situated. The book, being read, was to be rolled up again, and then a stone tied to it, and cast into the middle of the river, where the waters were deepest, and from whence it could not be taken up; and this was a sign confirming the above prophecy; compare with this what was done by a mighty angel concerning mystical Babylon, in which there is an allusion to this, ( Revelation 18:21 ) .

Jeremiah 51:63 In-Context

61 And Jeremy said to Seraiah, When thou comest into Babylon, and seest, and readest all these words,

62 thou shalt say, Lord, thou spakest against this place, that thou shouldest lose it, that none be that dwell therein, from man unto beast, and that it be an everlasting wilderness. (thou shalt say, O Lord, thou hast spoken against this place, that thou wouldest destroy it, so that there be no one who live there, from man unto beast, and that it become an everlasting wilderness.)

63 And when thou hast [ful]filled to read this book, thou shalt bind to it a stone, and thou shalt cast it forth into the midst of Euphrates; (And when thou hast finished reading this book, thou shalt bind it to a stone, and thou shalt throw it forth into the midst of the Euphrates River;)

64 and thou shalt say, So Babylon shall be drowned, and it shall not rise from the face of torment, which I (shall) bring [up]on it, and it shall be destroyed. Hitherto be the words of Jeremy (Heretofore be the words of Jeremiah).