Ephesians 6:18

18 And pray in the Spirit on all occasions with all kinds of prayers and requests. With this in mind, be alert and always keep on praying for all the Lord’s people.

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Ephesians 6:18 in Other Translations

KJV

18 Praying always with all prayer and supplication in the Spirit, and watching thereunto with all perseverance and supplication for all saints;

ESV

18 praying at all times in the Spirit, with all prayer and supplication. To that end keep alert with all perseverance, making supplication for all the saints,

NLT

18 Pray in the Spirit at all times and on every occasion. Stay alert and be persistent in your prayers for all believers everywhere.

MSG

18 In the same way, prayer is essential in this ongoing warfare. Pray hard and long. Pray for your brothers and sisters. Keep your eyes open. Keep each other's spirits up so that no one falls behind or drops out.

CSB

18 With every prayer and request, pray at all times in the Spirit, and stay alert in this, with all perseverance and intercession for all the saints.

Ephesians 6:18 Meaning and Commentary

Ephesians 6:18

Praying always with all prayer and supplication in the
spirit
The last weapon is prayer, and takes in all sorts of prayer, mental and vocal, public and private; and every branch of it, as deprecation of evils, petitions for good things, and thanksgiving for mercies: and which should be used always: this stands opposed to such who pray not at all, or who have prayed, but have left it off; or who pray only in distress, and it suggests, that a man should pray as often as he has an opportunity; and particularly, that he should make use of it in times of darkness, desertion, and temptation: and this, when performed aright, is performed "in the Spirit"; with the heart, soul, and spirit engaged in it; it is put up with a true heart, and a right spirit, and without hypocrisy; in a spiritual way, and with fervency, and under the influence, and by the assistance of the Spirit of God.

And watching thereunto;
either to the word, as a direction for prayer, or to prayer itself; for opportunities to pray for the assistance of the Spirit in prayer, for an answer of it, and to return thanks for blessings when bestowed; and against all dependence on it, and against Satan's temptations, and our own corruptions with respect to it:

with all perseverance;
in it, notwithstanding what Satan and an unbelieving heart may suggest to the contrary:

and supplication for all saints;
of every nation, age, sex, and condition, in all places, and of every denomination. So Christ taught his disciples to pray, saying, our Father, suggesting, that they were not only to pray for themselves, but for all the children of God.

Taken from John Gill's Exposition of the Bible

Ephesians 6:18 In-Context

16 In addition to all this, take up the shield of faith, with which you can extinguish all the flaming arrows of the evil one.

17 Take the helmet of salvation and the sword of the Spirit, which is the word of God.

18 And pray in the Spirit on all occasions with all kinds of prayers and requests. With this in mind, be alert and always keep on praying for all the Lord’s people.

19 Pray also for me, that whenever I speak, words may be given me so that I will fearlessly make known the mystery of the gospel,

20 for which I am an ambassador in chains. Pray that I may declare it fearlessly, as I should.