Genesis 48:4

4 and said to me, Behold, I will increase thee, and multiply thee, and will make of thee multitudes of nations; and I will give this land to thee, and to thy seed after thee, for an everlasting possession.

Genesis 48:4 Meaning and Commentary

Genesis 48:4

And said unto me, behold, I will make thee fruitful
In a spiritual sense, in grace and good works; in a literal sense, in an increase of worldly substance, and especially of children: and multiply thee;
make his posterity numerous as the sand of the sea: and I will make of thee a multitude of people;
a large nation, consisting of many tribes, even a company of nations, as the twelve tribes of Israel were; and I will give this land unto thy seed after thee, [for] an
everlasting possession;
the land of Canaan, they were to possess as long as they were the people of God, and obedient to his law; by which obedience they held the land, even unto the coming of the Messiah, whom they rejected, and then they were cast out, and a "Loammi" (i.e. not my people, ( Hosea 1:9 ) ) written upon them, and their civil polity, as well as church state, at an end: and besides, Canaan was a type of the eternal inheritance of the saints in heaven, the spiritual Israel of God, which will be possessed by them to all eternity.

Genesis 48:4 In-Context

2 And it was reported to Jacob, saying, Behold, thy son Joseph cometh to thee; and Israel having strengthened himself, sat upon the bed.
3 And Jacob said to Joseph, My God appeared to me in Luza, in the land of Chanaan, and blessed me,
4 and said to me, Behold, I will increase thee, and multiply thee, and will make of thee multitudes of nations; and I will give this land to thee, and to thy seed after thee, for an everlasting possession.
5 Now then thy two sons, who were born to thee in the land of Egypt, before I came to thee into Egypt, are mine; Ephraim and Manasse, as Ruben and Symeon they shall be mine.
6 And the children which thou shalt beget hereafter, shall be in the name of their brethren; they shall be named after their inheritances.

The Brenton translation of the Septuagint is in the public domain.