Trouble and anguish have taken hold on me
Or, "found me" F1. Outward troubles and inward
distress; troubles arising from his enemies, the men of the
world, that hated and persecuted him; and from a body of sin and
death, from the temptations of Satan, and divine desertions; some
from without, and others from within; troubles both of body and
mind, which is what all good men are liable to;
[yet] thy commandments [are] my delights;
so far from being grievous, that they were a pleasure to him;
yea, exceedingly delighted him, and cheered and refreshed his
spirits amidst all his troubles.