The deaconess Olympias to whom seventeen of Chrysostom's extant letters are addressed was the most eminent of his female friends. She belonged to a Pagan family of high rank, and was born about 368. Her father Seleucus who was a count of the Empire died when she was a young girl and she was brought up under the guardianship of an uncle Procopius, who has a devout Christian and a friend of Gregory of Nazianzus. Gregory took great interest in her, speaking of her in his letters as "his own Olympias" and delighting to be addressed by her as "father." Her governess Theodosia, sister of St. Amphilochius of Iconium, was a woman whom Gregory exhorted her to imitate as the very pattern of Christian goodness. The orphan girl had great personal beauty, and was the heiress of a large fortunate. Naturally therefore she had many suitors, and in 384 at the age of sixteen she was wedded to Nerbridius, a young man of high rank and irreproachable character. The marriage however does not seem to have been a happy one, and perhaps in this fact as well as in the death of her husband about two years after their union, Olympias saw a divine intimation that she should not entangled herself again in the worldly cares and anxieties incident to married life. The Emperor Theodosius wished to unite her to a young Spaniard, Elpidius, a kinsman of his own, and irritated by her refusal, ordered her property to be confiscated until she should have attained her thirtieth year, unless she consented to the proposed union. Olympias however remained inflexible and in a letter of dignified sarcasm thanked the Emperor for relieving her from a heavy burden. "He could not have conferred a greater blessing upon her unless he had ordered her wealth to be bestowed upon the Churches and the poor." Theodosius perceiving the uselessness, if not regretting the injustice, of his harsh decree, cancelled it, and left her in the undisturbed enjoyment of her property. Henceforward her time and wealth were devoted to the service of religion. She ministered to the necessities of the sick and poor, and supported the work of the Church in Greece, Asia Minor and Syria with such lavish donations, not only her money but her land, that even Chrysostom, who might be called the great preacher of almsgiving, warned her against indiscriminate liberality, reminding her that as her wealth was a trust committed to her by God she ought to be discreet in the management of it. This salutary advice gained hin the ill-will of many avaricious bishops and clergy who had profited, or hoped to profit, by her gifts. She in her turn requited the Archbishops for his spiritual care by many little feminine attention to his bodily wants, especially by seeing that he was supplied with wholesome food, and did not over strained feeble constitution by a too rigid abstinence. She herself however practised the most austere asceticism, renouncing the luxury of the bath, wearing non but old course clothing, and subjecting herself to severe restrictions in respect of food and sleep.
After the expulsion of Chrysostom from Constantinople 404, through he intrigues of his enemies, Olympias suffered much from the persecution to which all his followers where subjected. She was accused of having been concerned in causing the fire which broke out immediately after his departure, and destroyed the Cathedral Church and the Senate House. Her intrepid demeanour before the praefect who tried in vain to frighten her into a confession of guilt, or induce her to acknowledge Arsacius who had been intruded into the See by an arbitrary exercise of imperial power, excited general admiration; and the tidings of her fortitude were a great consolation to the exiled archbishop in the midst of much bodily suffering, and mental distress. It is not quite certain whether she was driven from Constatinople or voluntarily retired from it; nor have we any definite information concerning the remainder of her life.