What are the references to Giants in the Bible? Whether an implication to the size or character of a man, there are numerous mentions of Giants in the Bible. Interestingly, giants weren't always cast in a positive manner as Goliath, from the story of David and Goliath, was struck down by the sling-shot of David. Giants in the Bible could also reference men that were simply tall compared to most of the people of Biblical times. Discover more about Giants in the Bible from this collection of scripture quotes!